An emerging body of research has explored the potential ergogenic effects of noninvasive interset recovery strategies involving the application of cold substances to the extremities distal to exercising muscles (e.g., palms of the hands or the soles of the feet). It was suggested that such strategies may acutely enhance resistance training (RT) performance by augmenting excitation and motor unit recruitment of the working muscles through enhanced stimulation of the central nervous system, resulting in greater force production and the ability to perform more repetitions to fatigue. Moreover, peripheral stimuli such as distal cooling may acutely reduce the sensation of distress during RT, allowing individuals to tolerate more exercise and achieve higher training volumes. Although there is some evidence that interset distal cooling confers an ergogenic benefit during RT, certain methodological considerations, a paucity of longitudinal research, and contrasting findings call into question its effectiveness. Thus, the purpose of this review is to assess the current evidence regarding the effects of interset palm and sole cooling on RT performance outcomes.

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Resistance training (RT) is a nonpharmacological complement to cancer treatments due to its effectiveness in attenuating sarcopenia, cardiotoxicity, fatigue, and emotional disorders common in oncology patients. To adequately program and evaluate the acute or long-term effects of this type of training, a proper evaluation of the patients’ strength levels is necessary. Strength evaluations traditionally applied to this population required reaching muscle or technical failure, which could increase their discomfort levels, risk of injury, or other complications associated with the disease. In this regard, this manuscript described different dynamic and isometric evaluations recommended to accurately and safely evaluate the strength of the oncology population. Concerning dynamic evaluations, the velocity based method is recommended to determine the capacity of the patient to apply force against maximal (i.e., 1 repetition maximum) and submaximal loads. The sit-to-stand or vertical jump tests are also proposed as alternatives to evaluate dynamic strength using body weight. For isometric assessments, the knee extension and handgrip tests could complement dynamic evaluations or replace them for patients with very low strength levels. Besides describing in depth the aforementioned evaluations, the current review proposes important methodological aspects to ensure their accurate, reliable, and safe implementation.

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