Training Clients with Multiple Sclerosis – Evidence-Based Recommendations

by Kristin Mendez, CSCS
Personal Training Quarterly June 2022
Vol 9, Issue 1


This article aims to help personal trainers understand the unique symptoms accompanying multiple sclerosis, how exercise recommendations change based on disease progression, and which techniques to best program for your client.

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This article originally appeared in Personal Training Quarterly (PTQ)—a quarterly publication for NSCA Members designed specifically for the personal trainer. Discover easy-to-read, research-based articles that take your training knowledge further with Nutrition, Programming, and Personal Business Development columns in each quarterly, electronic issue. Read more articles from PTQ »



1. Beier, ML. Multiple sclerosis and mental health: 3 common challenges. Johns Hopkins Medicine. Retrieved 2022 from https:// multiple-sclerosis-ms/multiple-sclerosis-and-mental-health-3- common-challenges.

2. Ghahfarrokhi, MM, Banitalebi, E, Negaresh, R, and Motl, RW. Home-based exercise training in multiple sclerosis: A systematic review with implications for future research. Multiple Sclerosis and Related Disorders 55: 103177, 2021.

3. Gheitasi, M, Bayattork, M, Andersen, LL, Imani, S, and Daneshfar, A. Effect of twelve weeks pilates training on functional balance of male patients with multiple sclerosis: Randomized controlled trial. Journal of Bodywork and Movement Therapies 25: 41-45, 2021.

4. Grazioli, E, Tranchita, E, Borriello, G, Cerulli, C, Minganti, C, and Parisi, A. The effects of concurrent resistance and aerobic exercise training on functional status in patients with multiple sclerosis. Current Sports Medicine Reports 18(12): 452-457, 2019.

5. Kalb, R, Brown, TR, Coote, S, Costello, K, Dalgas, U, Garmon, E, et al. Exercise and lifestyle physical activity recommendations for people with multiple sclerosis throughout the disease course. Multiple Sclerosis Journal 26(12): 1459-1469, 2020.

6. Keytsman, C, Van Noten, P, Verboven, K, Van Asch, P, and Eijnde, BO. Periodized versus classic exercise therapy in multiple sclerosis: A randomized controlled trial. Multiple Sclerosis and Related Disorders 49: 102782, 2021.

7. National Multiple Sclerosis Society. Exercise and physical activity recommendations for all people with MS: Guidelines and videos available. National Multiple Sclerosis Society. May 2020. Retrieved 2022 from https://www.nationalmssociety. org/About-the-Society/News/Exercise-and-Physical-Activity- Recommendations-for.

8. National Multiple Sclerosis Society. Types of MS. Retrieved 2022 from MS/Types-of-MS.

9. National Multiple Sclerosis Society. What is MS. Retrieved 2022 from

10. Torres-Costoso, A, Martínez-Vizcaíno, V, Reina-Gutiérrez, S, Álvarez-Bueno, C, Guzmán-Pavón, MJ, Pozuelo-Carrascosa, DP, et al. Effect of exercise on fatigue in multiple sclerosis: A network meta-analysis comparing different types of exercise. Archives of Physical Medicine and Rehabilitation 1-18, 2021.

11. Walton-Fisette, JL, and Wuest, DA. Foundations of Physical Education, Exercise Science, and Sport. McGraw-Hill Education, 2021.

About the author

Kristin Mendez, CSCS

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Kristin Mendez is an exercise physiologist and researcher inAthens, GA. She is currently pursuing her PhD in Kinesiology at theUniversity of Georgia. ...

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